XR 3054

XR 3054

• CAS Number: 247090-97-7
• UNSPSC Description: XR 3054 is an inhibitor for Farnesyl Transferase, that inhibits farnesylation of CAAX recognition peptide with IC50 of 50 μM. XR 3054 suppresses the farnesylation of p21 ras and activation of MAP kinase. XR 3054 inhibits the proliferation of prostate cancer cell and colon cancer cell, with IC50 of 8.8-21.4 μM[1].
• Target Antigen: Farnesyl Transferase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/xr-3054.html
• Smiles: C=C(C)[C@H]1CC[C@]2(COC(C)(O2)C)CC1
• Molecular Weight: 210.31
• References & Citations: [1]Donaldson MJ, et al., XR3054, structurally related to limonene, is a novel inhibitor of farnesyl protein transferase. Eur J Cancer. 1999 Jun;35(6):1014-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported