YM-58483

CAT: 0400-SIH-606-25MGSize: 25 mgDry Ice: NoHazardous: No
CAT#:0400-SIH-606-25MGSize:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
YM-58483 is a calcium release-activated calcium channel blocker. It inhibits antigen-induced histamine release via modulation of mast cell responses. It also is a potent T-cell antiproliferative agent.
Description
CRAC channel blocker
CAS Number
223499-30-7
Product Name Alternative
N-[4-[3,5-Bis (trifluoromethyl) -1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide; BTP2
UNSPSC
41116105
Type
Blocker
Source
Synthetic
Field of Research
Neuroscience | Neurotransmission | Ion Channels | Calcium Channels
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.005
Format
Off-white powder
Solubility
May be dissolved in DMSO (40 mg/ml)
Molecular Formula
C15H9F6N5OS
Molecular Weight
421.3
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Zitt. C., et al. (2004) J. Biol. Chem. 279(13): 12427-12437. 2. Law M., et al. (2001) Int. J. Biochem. Cell Biol. 43:1228-1239. 3. K Ohga et al. (2008) Int. Immunopharmacol. 8:1787-1792.