AJG049 (free base)

AJG049 (free base)

• CAS Number: 195991-49-2
• UNSPSC Description: AJG049 free base is a calcium channel (Ca2+ channel) antagonist. AJG049 free base regulates vascular relaxation, reduces cardiac load, and improves cardiac perfusion by binding to the binding site of L-type calcium channels, specifically Diltiazem (HY-B0632). AJG049 free base can be used in cardiovascular disease research[1].
• Target Antigen: Calcium Channel
• Type: Reference compound
• Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/ajg049-free-base.html
• Smiles: COC(C=C1)=CC=C1CCN(CCC2)[C@H]2CN3C4=CC=CC=C4COC5=CC=CC=C53
• Molecular Weight: 414.54
• References & Citations: [1]Hashimoto M, et al. Comparative studies of AJG049, a novel Ca2+ channel antagonist, on voltage-dependent L-type Ca2+ currents in intestinal and vascular smooth muscle. Br J Pharmacol. 2006 Sep;149(2):155-62.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported