TRPC6 Antibody - middle region

• Gene Name:

  Transient receptor potential cation channel, subfamily C, member 6

• Gene Aliases:

  TRP6, FSGS2

• Gene ID:

  7225

• Swiss Prot:

  Q9Y210

• Accession Number:

  NP_004612

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Yeast

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human TRPC6

• Target:

  TRPC6 forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .

• Partner Proteins:

  RNF24; TRPC3; ORAI1; TRPM2; TRPC6; SRC; ITPR3; MX1; FYN; TRPC7; TRPC5; TRPC4; TRPC1; TRPC2; ITPR1

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  KKGFQEDAEMNKINEEKKLGILGSHEDLSKLSLDKKQVGHNKQPSIRSSE

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 100%; Rat: 77%; Yeast: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  106kDa

• Protein Length:

  931

• NCBI Gene Symbol:

  TRPC6

• Host or Source:

  Rabbit

• Protein Name:

  Short transient receptor potential channel 6

• Gene Name URL:

  TRPC6

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_004621