TRPC6 Antibody

CAT: 0223-79-629Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0223-79-629Size:0.1 mg
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Background
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2) .
NCBI Gene ID
7225
Swiss Prot
Q61143
Accession Number
NP_004612.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
TRPC6 antibodypeptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
100 kDa
Specificity
This antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
TRPC6
NCBI Official Name
Transient receptor potential cation channel, subfamily C, member 6
NCBI Organism
Peptide Corresponding to the amino terminal sequence derived from mouse TRPC6.
Background Reference 01
Koichiro Kuwahara et al. (2006) J Clin Invest. 116 (12) : 3114–3126. Mark Estacion et al. (2006) J Physiol. 2006, 572 (Pt 2) : 359–377. Maria A et al. (2006) Proc Natl Acad Sci U S A. 103 (44) : 16586–16591.
Other Product Names
TRP6, FSGS2, TRP6, FLJ11098
Tested Applications
WB
Protein ID
5730102
Physical Properties
Liquid

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