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TRPC6 Antibody

CAT: 0247-OAPB00441-100UGSize: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0247-OAPB00441-100UGSize:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Transient receptor potential cation channel subfamily C member 6
Gene Aliases
Focal segmental glomerulosclerosis 2; FSGS2; short transient receptor potential channel 6; transient receptor protein 6; TRP6; TRP-6.
Gene ID
7225
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH93658
Reactivity
Human|Mouse
Immunogen
TRPC6 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human TRPC6. The immunogen is located within amino acids 50 - 100 of TRPC6.
Target
Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369) . Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346) . Seems not to be activated by intracellular calcium store depletion.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Homology
Human; Mouse
Format
Liquid. TRPC6 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution
TRPC6 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
NCBI Gene Symbol
TRPC6
Host or Source
Rabbit
Protein Name
Short transient receptor potential channel 6|Transient receptor potential cation channel, subfamily C, member 6 [Homo sapiens]
Gene Name URL
TRPC6
Nucleotide Accession Number
NM_004621.5

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