TRPC6 Antibody

• Gene Name:

  Transient receptor potential cation channel subfamily C member 6

• Gene Aliases:

  Focal segmental glomerulosclerosis 2; FSGS2; short transient receptor potential channel 6; transient receptor protein 6; TRP6; TRP-6.

• Gene ID:

  7225

• Accession Number:

  NP_004612.2

• Reactivity:

  Human|Mouse

• Immunogen:

  This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to a region near the carboxy terminus of human TRPC6 protein.

• Target:

  Thought to form a receptor-activated non-selective calcium permeant cation channel (PubMed:19936226, PubMed:23291369) . Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C (PubMed:26892346) . Seems not to be activated by intracellular calcium store depletion.

• Clonality:

  Monoclonal

• Clone:

  3F2.H10.F2

• Conjugation:

  Unconjugated

• Type:

  Monoclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Homology:

  Human

• Format:

  Liquid (sterile filtered)

• Reconstitution:

  -20°C|See manual

• NCBI Gene Symbol:

  TRPC6

• Host or Source:

  Mouse

• Protein Name:

  Short transient receptor potential channel 6

• Gene Name URL:

  TRPC6

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_004621.5