VH-298

CAT: 0931-TQ0121-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0931-TQ0121-01Size:2 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2097381-85-4

Target

Ligand for E3 Ligase, HIF/HIF Prolyl-Hydroxylase, HIF

Related Pathways

Angiogenesis, PROTAC, Metabolism, Chromatin/Epigenetic

Purity

>99.99%

Bioactivity

VH-298 is a potent inhibitor of VHL that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, that is the blockade of the VHL:HIF-α protein-protein interaction downstream of HIF-α hydroxylation by PHD enzymes.

Smiles

Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1

Molecular Formula

C27H33N5O4S

Molecular Weight

523.65

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T8966-01	ML-298
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Alternative Products

Catalog	Name
MBS3603305-01	VH 298
BUP10105-01	VH-298
HY-100947A-01	Cis VH-298
HY-100947R	VH-298 (Standard)
A20326-50	VH-298 50mg
A20326-25	VH-298 25mg
A20326-10	VH-298 10mg
A20326-2	VH-298 2mg
A20326-100	VH-298 100mg
A20326-5	VH-298 5mg

VH-298

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