BAY-298

CAT: 0931-T10469-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T10469-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2471978-97-7
Target
GNRH Receptor|||Others
Related Pathways
GPCR/G Protein|||Others
Bioactivity
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1].
Smiles
Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1
Molecular Formula
C27H21ClFN3O2
Molecular Weight
473.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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