BAY-298

• Target :

  GNRH Receptor|||Others

• Related Pathways :

  GPCR/G Protein|||Others

• Bioactivity :

  BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC50s of 96 nM, 23 nM, and 78 nM for hLH (human LH), rLH (rat LH), and cLH (cynomolgus monkey LH), respectively. It is the first nanomolar hLH-R antagonist that reduces sex hormone levels in vivo [1].

• Smiles :

  Fc1ccc(Oc2ccc(NC(=O)N3CCc4ncccc4[C@@H]3c3ccc(Cl)cc3)cc2)cc1

• Molecular Formula :

  C27H21ClFN3O2

• Molecular Weight :

  473.93

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2471978-97-7