VH-N412

• Target:

  LDLR

• Related Pathways:

  Metabolism

• Bioactivity:

  VH-N412 is a carrier-modified neurotrophin (NT) known for its excellent ability to penetrate the blood-brain barrier. This compound actively binds to both low-density lipoprotein receptor (LDLR) and neurotropin receptor 1 (NTSR-1), acting as an inducer of pharmacologically induced hypothermia (PIH) . Additionally, VH-N412 exhibits anticonvulsant and neuroprotective properties, making it a valuable agent for research in neurological disorders such as epilepsy.

• Smiles:

  C (N[C@@H] (CC1=CC=C (O) C=C1) C (N[C@H] (C (N[C@@H] (CC (C) C) C (O) =O) =O) [C@H] (CC) C) =O) (=O) [C@H]2N (C ([C@@H] (NC ([C@@H] (NC (CCOCCOCCOCCOCCOCCOCCNC (=O) [C@@H]3CSSC[C@@H] (NC (CC) =O) C (=O) N[C@@H] (CCSC) C (=O) N4[C@] (C (=O) N[C@@H] (CCCNC (=N) N) C (=O) N[C@@H] (CC (C) C) C (=O) N[C@@H] (CCCNC (=N) N) C (=O) N (C) CC (=O) N3) (CCCC4) [H]) =O) CCCNC (=N) N) =O) CCCNC (=N) N) =O) CCC2

• Molecular Formula:

  C94H163N27O24S3

• Molecular Weight:

  2151.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1801681-81-1