Uroguanylin (human)

• Target:

  Guanylate cyclase

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  Uroguanylin (human) serves as a natural ligand for the Guanylyl Cyclase C (GCC) receptor in metastatic colorectal cancer tumors and exhibits anti-tumor effects in an animal model of human colon cancer [1] [2].

• Smiles:

  N(C([C@@H](NC([C@@H](NC([C@H](CC(N)=O)N)=O)CC(O)=O)=O)CC(O)=O)=O)[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]2(C(=O)N[C@@H]([C@H](C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H](C)C(=O)N[C@@](CSSC1)(C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC(=O)N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CSSC2)[H])[H])[H]

• Molecular Formula:

  C64H102N18O26S4

• Molecular Weight:

  1667.86

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  154525-25-4