Cyclic MKEY

• Target :

  CXCR

• Related Pathways :

  GPCR/G Protein|||Autophagy|||Immunology/Inflammation

• Bioactivity :

  MKEY, a synthetic cyclic peptide inhibitor of CXCL4-CCL5 heterodimer formation, has been shown to protect against atherosclerosis and aortic aneurysm formation by mediating inflammation, but whether it modulates neuroinflammation and brain injury has not been studied.

• Smiles :

  [C@@H](CC1=CC=CC=C1)(NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](NC([C@@H](NC([C@H](CS)N)=O)CCCCN)=O)CCC(O)=O)=O)=O)C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CS)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)C(C)C)=O)=O)[C@H](C)C)=O)[C@@H](C)C)=O)C)=O)CC(C)C)=O)CC(N)=O)=O)CO)=O)CO)=O)CCCCN)=O)CO)=O)CO)=O)[C@@H](C)O)=O)=O

• Molecular Formula :

  C113H174N28O34S2

• Molecular Weight :

  2532.89

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  934385-55-4