Cyclic tri-AMP

• Target:

  Endonuclease

• Related Pathways:

  Cell Cycle/Checkpoint

• Bioactivity:

  Cyclic tri-AMP is a key element of the cyclic oligonucleotide-based anti-phage signaling system (CBASS), functioning as a second messenger in the immune defense against viral infections. It activates DNA endonuclease NucC through binding, leading to cell death and demonstrating antiviral properties.

• Smiles:

  O[C@H]1[C@H] (N2C=3C (N=C2) =C (N) N=CN3) O[C@]4 ([C@]1 (OP (=O) (O) OC[C@@]5 ([C@] ([C@@H] (O) [C@@H] (O5) N6C=7C (N=C6) =C (N) N=CN7) (OP (=O) (O) OC[C@@]8 ([C@@] (OP (=O) (O) OC4) ([C@@H] (O) [C@@H] (O8) N9C=%10C (N=C9) =C (N) N=CN%10) [H]) [H]) [H]) [H]) [H]) [H]

• Molecular Formula:

  C30H36N15O18P3

• Molecular Weight:

  987.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  54447-85-7