MRT-81

• Target:

  Hedgehog/Smoothened|||Smo

• Related Pathways:

  GPCR/G Protein|||Stem Cells

• Purity:

  0.9972

• Bioactivity:

  MRT-81 is a potent antagonist of human and rodent smoothened receptors that inhibits hedgehog activity with an IC50 value of 41 nM in Shh-light2 cells.It is used in the study of cancer.

• Smiles:

  COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1ccc(C)c(NC(=O)c2ccc(cc2)-c2ccccc2)c1

• Molecular Formula:

  C31H29N3O5S

• Molecular Weight:

  555.64

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1263132-08-6