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MRT-81

CAT: 0931-T9532-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9532-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1263132-08-6
Target
Hedgehog/Smoothened, Smo
Related Pathways
GPCR/G Protein, Stem Cells
Purity
0.9972
Bioactivity
MRT-81 is a potent antagonist of human and rodent smoothened receptors that inhibits hedgehog activity with an IC50 value of 41 nM in Shh-light2 cells.It is used in the study of cancer.
Smiles
COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1ccc(C)c(NC(=O)c2ccc(cc2)-c2ccccc2)c1
Molecular Formula
C31H29N3O5S
Molecular Weight
555.64
Shipping Conditions
Ice Packs
Storage Temperature
-20°C