MRT-23227

CAT: 0931-T211823-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T211823-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3050683-03-6
Target
Molecular Glues
Related Pathways
PROTAC
Bioactivity
MRT-23227 is a molecular glue degrader targeting cereblon (CRBN) . It forms a ternary complex with CRBN and G3BP2, which activates the ubiquitin-proteasome system to degrade G3BP2. MRT-23227 shows potential for research in G3BP2-related cancers (such as breast cancer and lung cancer) and neurodegenerative diseases.
Smiles
O=C1NC(=O)C(C=2C=CC=C(C=3C=CC(OCC4=NN(C=C4)C)=CC3)C2Cl)CC1
Molecular Formula
C22H20ClN3O3
Molecular Weight
409.87
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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