MRT-23227

• Target :

  Molecular Glues

• Related Pathways :

  PROTAC

• Bioactivity :

  MRT-23227 is a molecular glue degrader targeting cereblon (CRBN) . It forms a ternary complex with CRBN and G3BP2, which activates the ubiquitin-proteasome system to degrade G3BP2. MRT-23227 shows potential for research in G3BP2-related cancers (such as breast cancer and lung cancer) and neurodegenerative diseases.

• Smiles :

  O=C1NC(=O)C(C=2C=CC=C(C=3C=CC(OCC4=NN(C=C4)C)=CC3)C2Cl)CC1

• Molecular Formula :

  C22H20ClN3O3

• Molecular Weight :

  409.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3050683-03-6