Thalidomide 4-fluoride

CAT: 0931-T7755Size: 500 mgDry Ice: NoHazardous: No
CAT#:0931-T7755Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
835616-60-9
Target
Autophagy|||Apoptosis|||IRAK|||Ligand for E3 Ligase
Related Pathways
Apoptosis|||Immunology/Inflammation|||NF-?B|||Autophagy|||PROTAC
Purity
0.9912
Bioactivity
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
Smiles
O=C1N(C(=O)C=2C1=CC=CC2F)C3C(=O)NC(=O)CC3
Molecular Formula
C13H9FN2O4
Molecular Weight
276.22
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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