Thalidomide 4-fluoride

• Target:

  Autophagy|||Apoptosis|||IRAK|||Ligand for E3 Ligase

• Related Pathways:

  Apoptosis|||Immunology/Inflammation|||NF-?B|||Autophagy|||PROTAC

• Purity:

  0.9912

• Bioactivity:

  Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.

• Smiles:

  O=C1N (C (=O) C=2C1=CC=CC2F) C3C (=O) NC (=O) CC3

• Molecular Formula:

  C13H9FN2O4

• Molecular Weight:

  276.22

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  835616-60-9