GNE-493

• Target:

  MTOR|||PI3K

• Related Pathways:

  PI3K/Akt/mTOR signaling

• Purity:

  0.98

• Bioactivity:

  GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3K?, PI3K?, PI3K?, PI3K? and mTOR, respectively.

• Smiles:

  CC(C)(O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cnc(N)nc1

• Molecular Formula:

  C17H20N6O2S

• Molecular Weight:

  372.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1033735-94-2