AMG-47a

• Target :

  Kras|||Ras|||JAK|||VEGFR|||p38 MAPK|||Src

• Related Pathways :

  Chromatin/Epigenetic|||MAPK|||Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling|||Stem Cells

• Purity :

  0.9807

• Bioactivity :

  AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.

• Smiles :

  Cc1ccc(cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1)C(=O)Nc1cccc(c1)C(F)(F)F

• Molecular Formula :

  C29H28F3N5O2

• Molecular Weight :

  535.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  882663-88-9