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PHA-767491 hydrochloride

CAT: 0931-T6940-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T6940-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
942425-68-5
Target
GSK-3, Apoptosis, CDK
Related Pathways
Stem Cells, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Apoptosis
Purity
0.9992
Bioactivity
PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM) . It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
Smiles
Cl.O=C1NCCc2[nH]c(cc12)-c1ccncc1
Molecular Formula
C12H12ClN3O
Molecular Weight
249.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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256228-01PHA 767491 hydrochloride
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A21395-25PHA-767491 hydrochloride 25mg
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A21395-200PHA-767491 hydrochloride 200mg
A21395-100PHA-767491 hydrochloride 100mg
A21395-10PHA-767491 hydrochloride 10mg
A21395-50PHA-767491 hydrochloride 50mg
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