PHA-680632

• Target :

  FGFR|||PLK|||Aurora Kinase

• Related Pathways :

  Chromatin/Epigenetic|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cell Cycle/Checkpoint

• Purity :

  0.9903

• Bioactivity :

  PHA-680632 is potent inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 27 nM, 135 nM and 120 nM, respectively. It has 10- to 200-fold higher IC50 for FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.

• Smiles :

  CCc1cccc(CC)c1NC(=O)N1Cc2[nH]nc(NC(=O)c3ccc(cc3)N3CCN(C)CC3)c2C1

• Molecular Formula :

  C28H35N7O2

• Molecular Weight :

  501.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  398493-79-3