PHA-665752

CAT: 0931-T6128-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T6128-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

477575-56-7

Target

C-Met/HGFR, Autophagy, Apoptosis, FGFR, VEGFR, Bcr-Abl

Related Pathways

Tyrosine Kinase/Adaptors, Autophagy, Angiogenesis, Cytoskeletal Signaling, Apoptosis

Purity

0.9935

Bioactivity

PHA-665752 is an effective, specific and ATP-competitive c-Met inhibitor (IC50: 9 nM), >50-fold selectivity for c-Met than STKs or RTKs.

Smiles

C(=C\1/C=2C(NC1=O)=CC=C(S(CC3=C(Cl)C=CC=C3Cl)(=O)=O)C2)\C4=C(C)C(C(=O)N5[C@@H](CN6CCCC6)CCC5)=C(C)N4

Molecular Formula

C32H34Cl2N4O4S

Molecular Weight

641.61

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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