Cilengitide TFA

• Target:

  Autophagy|||Integrin

• Related Pathways:

  Cytoskeletal Signaling|||Autophagy

• Bioactivity:

  Cilengitide is a potent integrin inhibitor for ?v?3 receptor and ?v?5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

• Smiles:

  OC(=O)C(F)(F)F.CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

• Molecular Formula:

  C29H41F3N8O9

• Molecular Weight:

  702.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  199807-35-7