Cilengitide TFA

CAT: 0931-T6806-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T6806-01Size:100 mg
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CAS Number
199807-35-7
Target
Autophagy|||Integrin
Related Pathways
Cytoskeletal Signaling|||Autophagy
Bioactivity
Cilengitide is a potent integrin inhibitor for ?v?3 receptor and ?v?5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
Smiles
OC(=O)C(F)(F)F.CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
Molecular Formula
C29H41F3N8O9
Molecular Weight
702.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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