Cilengitide

• Target:

  Apoptosis|||PD-1/PD-L1|||Integrin|||Autophagy|||STAT

• Related Pathways:

  Stem Cells|||Immunology/Inflammation|||Apoptosis|||Cell Cycle/Checkpoint|||Autophagy|||JAK/STAT signaling|||Cytoskeletal Signaling

• Purity:

  0.998

• Bioactivity:

  Cilengitide (EMD 121974) is a potent integrin inhibitor for the ?v?3/5 receptor (IC50: 4.1/79 nM, in cell-free assays) with approximately 10-fold selectivity against gpIIbIIIa.

• Smiles:

  CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O

• Molecular Formula:

  C27H40N8O7

• Molecular Weight:

  588.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  188968-51-6