WZ-3146

CAT: 0931-T6733-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T6733-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1214265-56-1
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling
Purity
0.9895
Bioactivity
WZ3146 is a mutant-selective irreversible inhibitor of EGFR (L858R) and EGFR (E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I) .
Smiles
CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Oc3cccc(NC(=O)C=C)c3)n2)cc1
Molecular Formula
C24H25ClN6O2
Molecular Weight
464.95
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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