AZD 3147

• Target:

  MTOR

• Related Pathways:

  PI3K/Akt/mTOR signaling

• Purity:

  0.9999

• Bioactivity:

  AZD 3147 is an inhibitor of mTORC with IC50s of 40.7 and 5.75 nM for mTORC1 and mTORC2. AZD 3147 shows IC50s of 912, 5495, 9333, and 6310 nM for PI3K?, PI3K?, PI3K?, and PI3K?, respectively.

• Smiles:

  S (=O) (=O) (C1 (CC1) C=2C=C (N=C (N2) C3=CC=C (NC (NCCO) =S) C=C3) N4[C@@H] (C) COCC4) C5CC5

• Molecular Formula:

  C24H31N5O4S2

• Molecular Weight:

  517.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1101810-02-9