WZ-2-033

• Target:

  STAT

• Related Pathways:

  JAK/STAT signaling|||Stem Cells

• Bioactivity:

  WZ-2-033 is a potent STAT3 inhibitor. It inhibits proliferation, colony survival, migration, and invasion of MDA-MB-231, HCC70, and MDA-MB231-4175 cells, with IC50 values of 0.7, 1.3, and 1.3 ?M respectively.

• Smiles:

  O=C(NC=1C=CC=2C=CS(=O)(=O)C2C1)CC3=C(N=C4C=C(OC)C=CN43)C5=CC=C(C=C5)C(F)(F)F

• Molecular Formula:

  C25H18F3N3O4S

• Molecular Weight:

  513.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2416196-47-7