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AZ-3146

CAT: 0026-B1145-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B1145-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ 3146 is a potent and selective Mps1 (monopolar spindle 1) kinase inhibitor (IC₅₀ = 35 nM). Shows selectivity over 46 other kinases including aurora kinase B and Cdk1. AZ 3146 overrides spindle assembly checkpoint and also interferes with chromosome alignment. It has shown to inhibit the recruitment of Mad1, 2 and centromere protein E (CENP-E) to kinetochores.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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441958-01AZ 3146
A11170-100AZ 3146 100mg
A11170-5AZ 3146 5mg
A11170-50AZ 3146 50mg
A11170-25AZ 3146 25mg
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