SKI II

• Target :

  Apoptosis|||S1P Receptor|||Wnt/beta-catenin

• Related Pathways :

  GPCR/G Protein|||Stem Cells|||Cytoskeletal Signaling|||Apoptosis

• Purity :

  0.9997

• Bioactivity :

  SKI II (SphK-I2) is a highly selective and non-ATP-competitive S1P receptor inhibitor (IC50: 0.5 ?M) while exhibiting no inhibitory action on other kinases including PKC?, PI3K, and ERK2.

• Smiles :

  Oc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2)cc1

• Molecular Formula :

  C15H11ClN2OS

• Molecular Weight :

  302.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  312636-16-1