SKI-I

• Target :

  Apoptosis|||Others|||S1P Receptor

• Related Pathways :

  GPCR/G Protein|||Others|||Apoptosis

• Bioactivity :

  SKI-I is a potent and selective inhibitor of human sphingosine kinase (SK), with an IC50 of 1.2 ?M for ST-hSK, and also inhibits hERK2 (IC50 = 11 ?M) . SKI-I induces apoptosis in tumor cell lines.

• Smiles :

  Oc1ccc2ccccc2c1\C=N\NC(=O)c1cc([nH]n1)-c1ccc2ccccc2c1

• Molecular Formula :

  C25H18N4O2

• Molecular Weight :

  406.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  306301-68-8