SKI-349

• Target :

  Akt|||mTOR|||S1P Receptor

• Related Pathways :

  GPCR/G Protein|||Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling

• Bioactivity :

  SKI-349 is a dual-target inhibitor of sphingosine kinase 1/2 (SPHK1/2) and microtubule assembly (MDA), exhibiting anticancer activity by inhibiting the vitality, invasion, and AKT/mTOR signaling pathway of liver cells [1] [2].

• Smiles :

  C(=O)(C=1SC(NC2=CC=C(OC)C=C2)=NC1N)C3=CC(OC)=C(OC)C=C3

• Molecular Formula :

  C19H19N3O4S

• Molecular Weight :

  385.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  727686-80-8