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EGFR-IN-48

CAT: 0931-T64255-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T64255-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, EGFR
Related Pathways
Angiogenesis, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors
Bioactivity
EGFR-IN-48 is a potent, orally active EGFR inhibitor that acts on EGFRd19/TM/CS (IC50: 0.193 nM), EGFRLR/TM/CS (IC50: 0.251 nM), EGFRWT (IC50: 10.4 nM) . EGFR-IN-48 is also able to inhibit EGFR-IN-48 also inhibits the proliferation of BaF3EGFR del19/T790M/C797S cells (IC50: 1.526 nM) and PC-9EGFR del19/T790M/C797S cells (IC50: 66.7 nM) .
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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