PU-48

• Target :

  Others|||Urea Transporter

• Related Pathways :

  Membrane transporter/Ion channel|||Others

• Bioactivity :

  PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 ?M, exhibiting a significant diuretic effect in mouse models without notable cytotoxicity. This compound has the potential for further development as a diuretic [1].

• Smiles :

  O=C(OC)C=1SC=2N=C3C=CC(OC)=CC3=CC2C1N

• Molecular Formula :

  C14H12N2O3S

• Molecular Weight :

  288.32

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  335394-78-0