PU-48

• Target:

  Others|||Urea Transporter

• Related Pathways:

  Membrane transporter/Ion channel|||Others

• Bioactivity:

  PU-48 is a potent inhibitor of urea transporters A (UT-A) with an IC50 value of 0.32 ?M, exhibiting a significant diuretic effect in mouse models without notable cytotoxicity. This compound has the potential for further development as a diuretic [1].

• Smiles:

  O=C (OC) C=1SC=2N=C3C=CC (OC) =CC3=CC2C1N

• Molecular Formula:

  C14H12N2O3S

• Molecular Weight:

  288.32

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  335394-78-0