B-Raf IN 9

• Target:

  Raf|||Apoptosis|||Others

• Related Pathways:

  Others|||Apoptosis|||MAPK

• Bioactivity:

  B-Raf IN 9 (compound 8b) is an effective B-Raf inhibitor (IC50=24.79 nM) that blocks the cell cycle at the G2/M phase, induces apoptosis, and exhibits potent anti-tumor activity on human prostate cancer PC-3 cells (IC50=7.83 ?M) .

• Smiles:

  O=C1N (N=C (CC1) C2=CC=C (NC (NC3=CC=CC=C3) =S) C=C2) C4=CC=CC=C4

• Molecular Formula:

  C23H20N4OS

• Molecular Weight:

  400.5

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2477725-18-9