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B-Raf IN 7

CAT: 0931-T60933-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60933-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2477725-07-6
Target
Others, Raf
Related Pathways
MAPK, Others
Bioactivity
B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor with an IC50 of 110.23 nM. It exhibits antitumor activity against colon carcinoma cells (HCT-116), mammary gland cells (MCF-7), hepatocellular carcinoma cells (HEPG-2), human cervical carcinoma cells (Hela), and human prostate cancer cells (PC-3), with IC50 values of 7.50, 9.87, 10.57, 11.63, and 12.83 μM, respectively [1].
Smiles
NC=1N(N=NC1C(OCC)=O)C2=CC=C(C=C2)C=3CCC(=O)NN3
Molecular Formula
C15H16N6O3
Molecular Weight
328.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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