CSF1R-IN-3

• Target:

  C-Fms|||CSF-1R

• Related Pathways:

  Tyrosine Kinase/Adaptors

• Purity:

  0.984

• Bioactivity:

  CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM. CSF1R-IN-3 has anti-proliferative activity against colorectal cancer cells. CSF1R-IN-3 exhibits anti-tumour effects and immune enhancing effects by inhibiting the migration of macrophages and inducing the reprogramming of M2-type macrophages to M1-type macrophages, thus exhibited activity against colorectal cancer cells.

• Smiles:

  CN1CCN (CC (=O) Nc2c (C) [nH]c (\C=C3/C (=O) Nc4cc (NC (=O) Nc5cc (on5) C (C) (C) C) ccc34) c2C) CC1

• Molecular Formula:

  C30H38N8O4

• Molecular Weight:

  574.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2760584-90-3