DX3-213B

• Target:

  Mitochondrial Metabolism|||OXPHOS

• Related Pathways:

  Metabolism|||Apoptosis

• Purity:

  0.9985

• Bioactivity:

  DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM. DX3-213B blocks ATP production (IC50: 11 nM) and inhibits the growth of MIA PaCa-2 cells (GI50: 11 nM) . DX3-213B can be used to study pancreatic cancer.

• Smiles:

  CC (C) S (=O) (=O) c1ccc (cc1) S (=O) (=O) N1CCC[C@H] (C1) C (=O) N1CCC (F) (F) CC1

• Molecular Formula:

  C20H28F2N2O5S2

• Molecular Weight:

  478.57

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2749555-66-4