BSJ-01-175

• CAS Number :

  2227392-55-2

• Target :

  Others|||CDK

• Related Pathways :

  Cell Cycle/Checkpoint|||Others

• Bioactivity :

  BSJ-01-175 is a selective and potent covalent inhibitor of CDK12/13. BSJ-01-175 is significantly selective for cancer cells, exhibits potent inhibition of phosphorylated RNA polymerase II, and significantly downregulates CDK12 target genes.

• Smiles :

  ClC=1C(C=2C=3C(NC2)=CC=CC3)=NC(N[C@H]4C[C@H](OC5=CC=C(NC(/C=C/CN(C)C)=O)C=C5)CCC4)=NC1

• Molecular Formula :

  C30H33ClN6O2

• Molecular Weight :

  545.08

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C