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BSJ-5-63

CAT: 0931-T88693-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T88693-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2519823-37-9
Target
CDK, PROTACs
Related Pathways
Cell Cycle/Checkpoint, PROTAC
Bioactivity
BSJ-5-63 is an effective degrader of CDK12, CDK7, and CDK9. It reduces the protein expression of CDK12, CDK7, CDK9, RNAPII, and Cyclin K, and also decreases the mRNA expression of BRCA1 and BRCA2. BSJ-5-63 exhibits anticancer activity and holds potential for prostate cancer research.
Smiles
C([C@@H](NC(CCCCCCCCCCN1C[C@H](NC=2N=C(NC3=C(S(C(C)C)(=O)=O)C=CC=C3)C(Cl)=CN2)CCC1)=O)[C@](C)(C)C)(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C=6SC=NC6C)=O)C[C@@H](O)C4
Molecular Formula
C52H74ClN9O6S2
Molecular Weight
1020.78
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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