BSJ-4-116

CAT: 0931-MF-0014849-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0014849-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2519823-34-6
Target
PROTACs|||CDK
Related Pathways
Cell Cycle/Checkpoint|||PROTAC
Purity
0.9909
Bioactivity
BSJ-4-116 is a highly potent and selective CDK12 degrader (PROTAC) with an IC50 of 6 nM. It downregulates DDR genes through a premature termination of transcription, primarily through increasing poly (adenylation) .
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCCCCN4C[C@H](NC=5N=C(NC6=C(S(C(C)C)(=O)=O)C=CC=C6)C(Cl)=CN5)CCC4)=O
Molecular Formula
C40H49ClN8O8S
Molecular Weight
837.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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