AMG 900

• Target :

  P38 MAPK|||Aurora Kinase|||Tyrosine Kinases

• Related Pathways :

  Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||MAPK|||Tyrosine Kinase/Adaptors

• Purity :

  0.9951

• Bioactivity :

  AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 values of 5 nM, 4 nM, and 1 nM, respectively. It exhibits over 10-fold selectivity for Aurora kinases compared to p38?, Tyk2, JNK2, Met, and Tie2. [Phase 1].

• Smiles :

  Cc1csc(c1)-c1nnc(Nc2ccc(Oc3ncccc3-c3ccnc(N)n3)cc2)c2ccccc12

• Molecular Formula :

  C28H21N7OS

• Molecular Weight :

  503.58

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  945595-80-2