AMG 517

• Target :

  TRP/TRPV Channel

• Related Pathways :

  Membrane transporter/Ion channel

• Purity :

  0.9985

• Bioactivity :

  AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.

• Smiles :

  O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)C4=CC=C(C(F)(F)F)C=C4

• Molecular Formula :

  C20H13F3N4O2S

• Molecular Weight :

  430.4

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  659730-32-2