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AMG 517

CAT: 0931-T6379-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T6379-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
659730-32-2
Target
TRP/TRPV Channel
Related Pathways
Membrane transporter/Ion channel
Purity
0.9985
Bioactivity
AMG 517 is an effective and specific TRPV1 antagonist, antagonizes proton (IC50: 0.76 nM), capsaicin (IC50: 0.62 nM), and heat activation (IC50: 1.3 nM) of TRPV1.
Smiles
O(C1=C2C(SC(NC(C)=O)=N2)=CC=C1)C=3C=C(N=CN3)C4=CC=C(C(F)(F)F)C=C4
Molecular Formula
C20H13F3N4O2S
Molecular Weight
430.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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