CCG-273220

• CAS Number :

  2750414-35-6

• Target :

  Others|||GRK

• Related Pathways :

  GPCR/G Protein|||Others

• Bioactivity :

  CCG-273220 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) (IC50: 220 nM) .CCG-273220 covalently binds the GRK5 subfamily-specific residue Cys474 and is more selective for GRK5 than GRK2.

• Smiles :

  C[C@@H](NC(=O)c1ccc2NC(=O)\C(=C/c3[nH]c(C)c(NC(=O)CCl)c3C)c2c1)c1ccc(F)cc1

• Molecular Formula :

  C26H24ClFN4O3

• Molecular Weight :

  494.95

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C