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DHODH-IN-20

CAT: 0931-T63148-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63148-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2639835-02-0
Target
Others, Dehydrogenase, DNA/RNA Synthesis
Related Pathways
Metabolism, Cell Cycle/Checkpoint, Others, DNA Damage/DNA Repair
Bioactivity
Dhodh-in-20 (Compound 133) is a potent inhibitor of DHODH. Among them, DHODH is an iron-containing flavin-dependent enzyme that is present in the inner membrane of human mitochondria. DHODH-IN-20 showed an inhibitory effect on tumor growth. DHODH-IN-20 has the potential to be used in the study of acute myeloid leukemia.
Smiles
FC=1C(C=2N=C(C(C)(C)O)N(C)C2)=CC(O[C@H](C(F)(F)F)C)=C(C(NC3=C(C)C=CC=C3)=O)C1
Molecular Formula
C24H25F4N3O3
Molecular Weight
479.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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