LU-005i

• CAS Number :

  1620107-33-6

• Target :

  Others|||Proteasome

• Related Pathways :

  Others|||Proteases/Proteasome|||Ubiquitination

• Bioactivity :

  LU-005i is a powerful inhibitor targeting the ?5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring ?5i over the ?5c subunit, which has an IC 50 value of 287 nM [1].

• Smiles :

  C([C@H](CC1CCCCC1)NC([C@H](CC2=CC=C(OC)C=C2)NC([C@@H](NC(CN3CCOCC3)=O)C)=O)=O)(=O)[C@@]4(C)CO4

• Molecular Formula :

  C31H46N4O7

• Molecular Weight :

  586.72

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C