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LU-005i

CAT: 0931-T84755-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T84755-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1620107-33-6
Target
Others, Proteasome
Related Pathways
Others, Proteases/Proteasome, Ubiquitination
Bioactivity
LU-005i is a powerful inhibitor targeting the β5i subunit of immunoproteasomes, displaying a high potency with an IC 50 value of 6.6 nM, and exhibits selectivity by preferring β5i over the β5c subunit, which has an IC 50 value of 287 nM [1].
Smiles
C([C@H](CC1CCCCC1)NC([C@H](CC2=CC=C(OC)C=C2)NC([C@@H](NC(CN3CCOCC3)=O)C)=O)=O)(=O)[C@@]4(C)CO4
Molecular Formula
C31H46N4O7
Molecular Weight
586.72
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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