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Dot1L-IN-7

CAT: 0931-T62915-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62915-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2580940-76-5
Target
Histone Methyltransferase, Others
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
Dot1L-IN-7 (compound 25) is a selective and potent inhibitor of telomere silencing 1-like protein (DOT1L) with an IC50 of 1.0 μM. It selectively kills MLL-AF9 cells without affecting the growth of E2A-HLF cells.
Smiles
C(CNC(CN1N=C(C(NC2=CC=C(C(C)(C)C)C=C2)=O)N=C1)=O)N3C=4C(C=C3)=C(N)N=CN4
Molecular Formula
C23H27N9O2
Molecular Weight
461.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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