Dot1L-IN-5

• Target:

  Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic

• Bioactivity:

  Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein (DOT1L) with an IC 50 SPA DOT1L of 0.17 nM [1].

• Smiles:

  COc1nc(N)nc(Nc2cc(ccc2N[C@@H](c2cccc3OC(F)(F)Oc23)c2ncccc2Cl)S(N)(=O)=O)n1

• Molecular Formula:

  C23H19ClF2N8O5S

• Molecular Weight:

  592.96

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2565705-03-3