Dot1L-IN-5

CAT: 0931-T11084-01Size: 25 mgDry Ice: NoHazardous: No
CAT#: T11084-01Size: 25 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2565705-03-3
Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
Dot1L-IN-5 is a potent inhibitor of the disruptor of telomeric silencing 1-like protein (DOT1L) with an IC 50 SPA DOT1L of 0.17 nM [1].
Smiles
COc1nc(N)nc(Nc2cc(ccc2N[C@@H](c2cccc3OC(F)(F)Oc23)c2ncccc2Cl)S(N)(=O)=O)n1
Molecular Formula
C23H19ClF2N8O5S
Molecular Weight
592.96
Shipping Conditions
Cool pack
Storage Temperature
-20°C