IMP-1700

CAT: 0931-T37729-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T37729-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1458674-25-3
Target
Others
Related Pathways
Others
Bioactivity
IMP-1700 is an inhibitor of bacterial DNA repair.1It potentiates the activity of the quinolone antibiotic ciprofloxacin against methicillin-resistantS. aureus (MRSA) with a combination index value of 0.7. IMP-1700 inhibits the ciprofloxacin-induced bacterial SOS response, a process that repairs DNA damage, in a reporter assay in a concentration-dependent manner. It is also active againstE. coli, as well as methicillin-resistant and -sensitive S. aureus, when used alone (EC50s = 0.5, 0.21, and 3.8 ?M, respectively) .
Smiles
OC(=O)c1cn(C2CC2)c2cc(N3CCN(CC3)C(=S)Nc3ccc(cc3)C(F)(F)F)c(F)cc2c1=O
Molecular Formula
C25H22F4N4O3S
Molecular Weight
534.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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