AMG-208

CAT: 0931-T6260-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0931-T6260-01Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1002304-34-8

Target

Cytochromes P450, c-Met/HGFR

Related Pathways

Metabolism, Tyrosine Kinase/Adaptors

Purity

0.9927

Bioactivity

AMG-208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1.

Smiles

COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccccc3)ccnc2c1

Molecular Formula

C22H17N5O2

Molecular Weight

383.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

1002304-34-8

PubChem

cas	1002304-34-8
modify	2026-05-17
description	AMG-208 is a member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer. It has a role as an antineoplastic agent and a c-Met tyrosine kinase inhibitor. It is a member of quinolines, an aromatic ether and a triazolopyridazine.
synonyms	AMG-2081002304-34-8AMG 208AMG208 7-methoxy-4-((6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy)quinoline Y2SR66P7VM 7-methoxy-4-[(6-phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline 7-methoxy-4-[(6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy]quinoline Quinoline, 7-methoxy-4-[(6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3-yl)methoxy]- AMG 208 [WHO-DD]+ 15 more
PubChem Link	Click here

Catalog	Name
A1186-25	AMG-208
MBS384185-01	AMG 208