NIC-0102

• Target:

  Others|||NOD-like Receptor (NLR) |||Proteasome

• Related Pathways:

  Others|||Ubiquitination|||Proteases/Proteasome|||Immunology/Inflammation

• Bioactivity:

  NIC-0102 is an orally active proteasome inhibitor (pIC50: 7.55) that specifically inhibits NLRP3 inflammatory vesicle activation.

• Smiles:

  C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)B(O)O)=O)(=O)C2=C(F)C=CC=C2F

• Molecular Formula:

  C21H25BF2N2O4

• Molecular Weight:

  418.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2806031-94-5