NIC-0102

• Target:

  Others|||NOD-like Receptor (NLR) |||Proteasome

• Related Pathways:

  Others|||Ubiquitination|||Proteases/Proteasome|||Immunology/Inflammation

• Bioactivity:

  NIC-0102 is an orally active proteasome inhibitor (pIC50: 7.55) that specifically inhibits NLRP3 inflammatory vesicle activation.

• Smiles:

  C (N[C@@H] (CC1=CC=CC=C1) C (N[C@@H] (CC (C) C) B (O) O) =O) (=O) C2=C (F) C=CC=C2F

• Molecular Formula:

  C21H25BF2N2O4

• Molecular Weight:

  418.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2806031-94-5