NIC-0102

• Target :

  Others|||NOD-like Receptor (NLR) |||Proteasome

• Related Pathways :

  Others|||Ubiquitination|||Proteases/Proteasome|||Immunology/Inflammation

• Bioactivity :

  NIC-0102 is an orally active proteasome inhibitor (pIC50: 7.55) that specifically inhibits NLRP3 inflammatory vesicle activation.

• Smiles :

  C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)B(O)O)=O)(=O)C2=C(F)C=CC=C2F

• Molecular Formula :

  C21H25BF2N2O4

• Molecular Weight :

  418.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2806031-94-5