WDR5-0102

CAT: 0931-T67947-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T67947-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
824960-50-1
Target
JAK|||Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic|||JAK/STAT signaling|||Stem Cells|||Angiogenesis|||Tyrosine Kinase/Adaptors
Purity
0.9803
Bioactivity
WDR5-0102 is a compound that inhibits the WDR5-MLL1 interface (K dis = 7 ?M, K d = 4 ?M), selectively reducing MLL1 HMT activity without affecting the human H3K4 methyltransferase SETD7 or other HMTs, including G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5.
Smiles
N(C(=O)C1=C(Cl)C=CC=C1)C2=C(C=CC(N(=O)=O)=C2)N3CCN(C)CC3
Molecular Formula
C18H19ClN4O3
Molecular Weight
374.82
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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